Middle East holds the most proven oil reserve, but its wars impact not only the local economy and politic stability, but also the global energy market, even China‘s energy security. This paper analyzes its position in global oil resource and China’s dependence, studies the relation between its politic evolution and global oil price, the relation between the global oil price fluctuation and China‘s oil price, and reviews its mess situation and trend, presents its influence on China’s energy supply and channels. China should pay more attention to the major oil producers and continental oil gas channels. Middle East should be a paramount mission for China‘s energy diplomacy regarding China’s energy security by using political, economic and diplomatic means.